Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202789 | 0.89 | CETP (0.47) | CETPKCNH2 | |
| SCHEMBL4640202 | 0.87 | CETP (0.43) | CETP | |
| SCHEMBL4717108 | 0.83 | CETP (0.50) | CETPKCNH2 | |
| SCHEMBL4639381 | 0.83 | KIF11 (0.44) | CETPKCNH2 | |
| SCHEMBL4639727 | 0.80 | CETP (0.49) | CETPKCNH2 | |
| SCHEMBL4639127 | 0.80 | CETP (0.53) | CETPKCNH2 | |
| SCHEMBL4640350 | 0.79 | CETP (0.51) | CETPKCNH2 | |
| SCHEMBL4640200 | 0.79 | CETP (0.49) | CETPKCNH2 | |
| SCHEMBL4640356 | 0.79 | NOS3 (0.39) | CETP | |
| SCHEMBL4720163 | 0.78 | CETP (0.65) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951673-A2 | HETEROCYCLIC CETP INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1951690-A1 | HETEROCYCLIC CETP INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007062342-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |