Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 17/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184057 | 0.82 | CETP (0.64) | CETPKCNH2 | |
| SCHEMBL1184059 | 0.82 | CETP (0.64) | CETPKCNH2 | |
| SCHEMBL4639381 | 0.81 | KIF11 (0.44) | CETPKCNH2 | |
| SCHEMBL4639671 | 0.75 | CETP (0.66) | CETP | |
| SCHEMBL4639179 | 0.75 | CETP (0.48) | CETPKCNH2 | |
| SCHEMBL4639127 | 0.74 | CETP (0.53) | CETPKCNH2 | |
| SCHEMBL4639158 | 0.73 | CETP (0.58) | CETP | |
| SCHEMBL4639284 | 0.73 | CETP (0.56) | CETP | |
| SCHEMBL4639196 | 0.73 | CETP (0.67) | CETP | |
| SCHEMBL4639792 | 0.72 | CETP (0.57) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951673-A2 | HETEROCYCLIC CETP INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |