Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46058 | 0.89 | KDM4E (0.34) | COMTPOLBMAPK8KMT2AMEN1 | |
| SCHEMBL12574766 | 0.87 | COMT (0.33) | COMTPOLBMAPK8KMT2AMEN1 | |
| SCHEMBL16456945 | 0.85 | FFAR4 (0.34) | COMTPOLBMAPK8KMT2AMEN1 | |
| SCHEMBL37524 | 0.84 | OPRM1 (0.33) | POLBMAPK8KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL37478 | 0.84 | MAPK8 (0.36) | COMTPOLBMAPK8KMT2AMEN1 | |
| SCHEMBL12574770 | 0.82 | RAB9A (0.34) | KMT2AMAPTKDM4EALDH1A1HTT | |
| SCHEMBL19139664 | 0.81 | POLB (0.35) | COMTPOLBMAPK8KMT2AMEN1 | |
| SCHEMBL46336 | 0.80 | MAPT (0.35) | COMTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13884156 | 0.79 | MAPK8 (0.39) | COMTPOLBMAPK8KMT2AMEN1 | |
| SCHEMBL19956367 | 0.78 | KMT2A (0.33) | POLBMAPK8KMT2AMEN1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010063670-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |