Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46058 | 0.91 | KDM4E (0.34) | MAPTCOMTKMT2AALDH1A1GAA | |
| SCHEMBL46128 | 0.87 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL46114 | 0.85 | MEN1 (0.33) | KMT2AALDH1A1MEN1 | |
| SCHEMBL46337 | 0.84 | OPRM1 (0.35) | MAPTKMT2ANPC1RAB9AP2RX7 | |
| SCHEMBL15032127 | 0.84 | RXFP1 (0.35) | MAPTGRIN2BCOMTKMT2AGAA | |
| SCHEMBL46350 | 0.83 | TSHR (0.31) | SMN1; SMN2 | |
| SCHEMBL12071754 | 0.83 | SIGMAR1 (0.33) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL46109 | 0.82 | SIGMAR1 (0.33) | KMT2AALDH1A1GAANPC1RAB9A | |
| SCHEMBL46051 | 0.82 | ERBB2 (0.30) | L3MBTL1 | |
| SCHEMBL46062 | 0.81 | KDM4E (0.32) | KMT2AALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |