Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637765 | 0.91 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP19A1PTGER4GAA | |
| SCHEMBL4637835 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP19A1PTGER4GAA | |
| SCHEMBL6230808 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP19A1PTGER4GAA | |
| SCHEMBL4637783 | 0.83 | TACR1 (0.41) | ALDH1A1TSHRCYP19A1PTGER4GAA | |
| SCHEMBL4638565 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP19A1PTGER4GAA | |
| SCHEMBL4639007 | 0.80 | GPBAR1 (0.37) | ALDH1A1TSHRCYP19A1TACR1GRM2 | |
| SCHEMBL4637701 | 0.78 | GPBAR1 (0.38) | ALDH1A1TSHRCYP19A1TACR1GRM2 | |
| SCHEMBL4705766 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP19A1PTGER4GAA | |
| SCHEMBL4638919 | 0.78 | TACR1 (0.48) | ALDH1A1TSHRCYP19A1GAATACR1 | |
| SCHEMBL4638479 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP19A1GAATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |