Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592936 | 0.82 | MAPK1 (0.55) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5592772 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4277052 | 0.77 | MAPK1 (0.50) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4271339 | 0.77 | KDM4E (0.53) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4271190 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4271199 | 0.75 | MAPK1 (0.48) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4278843 | 0.75 | MAPK1 (0.48) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL28034372 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4640428 | 0.74 | MAPK1 (0.47) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4278957 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-B1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |