Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639858 | 0.83 | S1PR1 (0.47) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL17360640 | 0.80 | HDAC1 (0.54) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28034372 | 0.77 | ALDH1A1 (0.56) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL28815027 | 0.76 | HDAC1 (0.37) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28787697 | 0.76 | FFAR1 (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL13701433 | 0.75 | MAPK1 (0.44) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL19194454 | 0.75 | MAPT (0.44) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL5592936 | 0.75 | MAPK1 (0.55) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL27516569 | 0.75 | LMNA (0.53) | ALDH1A1MAPTLMNAL3MBTL1NPC1 | |
| SCHEMBL4278957 | 0.75 | ALDH1A1 (0.60) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |