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Sulfamide

Sulfamide

SCHEMBL4639677

Cc1ccc(-c2nc(C(F)(F)F)cn2-c2ccccc2)cn1.NS(N)(=O)=O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 20/20 0.79
▸ PTGS1 P23219 12/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8593163 0.93 PTGS2 (0.73) PTGS2PTGS1
SCHEMBL215709 0.88 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL214170 0.86 PTGS2 (1.00) PTGS2PTGS1
Sulfamide SCHEMBL4639731 0.85 PTGS2 (0.82) PTGS2PTGS1
SCHEMBL5594366 0.82 PTGS2 (0.90) PTGS2PTGS1
SCHEMBL5594424 0.82 PTGS2 (0.90) PTGS2PTGS1
Sulfamide SCHEMBL4639682 0.81 PTGS2 (0.80) PTGS2PTGS1
Sulfamide SCHEMBL4638575 0.81 PTGS2 (0.80) PTGS2PTGS1
Sulfamide SCHEMBL4639044 0.80 PTGS2 (0.81) PTGS2PTGS1
Sulfamide SCHEMBL4639261 0.80 PTGS2 (0.80) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479385-B1 Use of cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia SEARLE LLC (US) 2008-07-02 — — EP claimed