Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639483 | 0.93 | KDM4E (0.44) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4639475 | 0.92 | KDM4E (0.38) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4640544 | 0.92 | PIK3CG (0.42) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4639429 | 0.91 | KDM4E (0.37) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4640424 | 0.84 | KDM4E (0.39) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4640577 | 0.83 | KDM4E (0.39) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4640423 | 0.83 | PDE4A (0.43) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4641365 | 0.82 | LMNA (0.38) | MAPTKDM4EHSD17B10USP2KMT2A | |
| SCHEMBL4639629 | 0.81 | PARP1 (0.44) | MAPTKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL4639574 | 0.81 | MAPT (0.37) | MAPTKDM4EHSD17B10USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |