Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918981 | 0.75 | ALDH1A1 (0.40) | CCR2HTT | |
| SCHEMBL1062408 | 0.73 | CCR2 (0.41) | CCR2 | |
| SCHEMBL1080106 | 0.73 | CCR2 (0.41) | CCR2 | |
| SCHEMBL1080108 | 0.72 | CCR2 (0.70) | CCR2 | |
| SCHEMBL1062410 | 0.72 | CCR2 (0.70) | CCR2 | |
| SCHEMBL16214717 | 0.71 | SLC6A3 (0.43) | CCR2HTTSLC6A3 | |
| SCHEMBL4618619 | 0.70 | KMT2A (0.37) | — | |
| SCHEMBL7421794 | 0.68 | BTK (0.44) | — | |
| SCHEMBL1114653 | 0.67 | CCR2 (0.40) | CCR2 | |
| SCHEMBL1272610 | 0.67 | CRBN (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896036-A1 | ANTI-INFLAMMATORY AGENTS | Cambridge Enterprise Limited (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006134384-A1 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2006-12-21 | — | — | WO | disclosed |