Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 6/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641257 | 0.93 | FPR2 (0.37) | HDAC1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL4639330 | 0.89 | KDM4E (0.35) | HDAC1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL5592932 | 0.88 | DHODH (0.41) | DCKHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4639629 | 0.87 | PARP1 (0.44) | KDM4ELMNAKMT2AMEN1USP2 | |
| SCHEMBL4271812 | 0.84 | KDM4E (0.41) | DCKHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4639422 | 0.83 | SMN1; SMN2 (0.42) | KDM4ELMNAFPR2USP2MAPT | |
| SCHEMBL4639865 | 0.82 | KDM4E (0.41) | HDAC1HDAC8HDAC6KDM4ELMNA | |
| SCHEMBL5592764 | 0.81 | PARP1 (0.39) | KDM4ELMNAKMT2AMEN1USP2 | |
| SCHEMBL5592687 | 0.81 | FPR2 (0.37) | KDM4ELMNAFPR2KMT2AMEN1 | |
| SCHEMBL4639554 | 0.81 | PARP1 (0.41) | KDM4ELMNAKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |