Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 7/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639814 | 0.93 | KDM4E (0.41) | NPSR1LMNAKDM4EMEN1USP2 | |
| SCHEMBL4639422 | 0.91 | SMN1; SMN2 (0.42) | FPR2NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL4641012 | 0.89 | TSHR (0.41) | PDE4DLMNAKDM4EMEN1USP2 | |
| SCHEMBL5592984 | 0.89 | LMNA (0.36) | NPSR1LMNAKDM4EMEN1USP2 | |
| SCHEMBL4641257 | 0.87 | FPR2 (0.37) | FPR2NPSR1KDM4E | |
| SCHEMBL5592932 | 0.87 | DHODH (0.41) | FPR2LMNAKDM4EMEN1USP2 | |
| SCHEMBL4639429 | 0.86 | KDM4E (0.37) | NPSR1LMNAKDM4EMEN1USP2 | |
| SCHEMBL4639868 | 0.86 | PDE4A (0.43) | FPR2PDE4DLMNAMAPT | |
| SCHEMBL4639603 | 0.85 | PDE4A (0.44) | PDE4D | |
| SCHEMBL4639471 | 0.85 | PDE4B (0.40) | FPR2PDE4DLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |