Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | DCK | P27707 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639772 | 0.88 | DCK (0.37) | DCKMAPTLMNAFPR2HDAC1 | |
| SCHEMBL5592687 | 0.87 | FPR2 (0.37) | MAPTLMNAFPR2KMT2AKDM4E | |
| SCHEMBL4639814 | 0.85 | KDM4E (0.41) | MAPTLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL5592984 | 0.84 | LMNA (0.36) | DHODHMAPTLMNAKMT2AKDM4E | |
| SCHEMBL4639422 | 0.84 | SMN1; SMN2 (0.42) | MAPTLMNAFPR2KDM4EUSP2 | |
| SCHEMBL4280381 | 0.83 | DHODH (0.43) | DHODHMAPTFPR2 | |
| SCHEMBL4641012 | 0.83 | TSHR (0.41) | MAPTLMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL4640424 | 0.81 | KDM4E (0.39) | MAPTLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL4641121 | 0.81 | KDM4E (0.42) | MAPTLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL4640577 | 0.81 | KDM4E (0.39) | MAPTLMNAKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |