SCHEMBL4639880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18963341	0.88	CNR2 (0.49)	CYP1A2CYP2C9ALDH1A1MRGPRX4SCN9A
	SCHEMBL3711919	0.86	MRGPRX4 (0.44)	CYP1A2CYP2C9KDM4EALDH1A1MRGPRX4
	SCHEMBL11786444	0.84	KDM4E (0.69)	CYP1A2CYP2C9KDM4EMAPTHTT
	SCHEMBL7336593	0.84	ALDH1A1 (0.52)	CYP1A2CYP2C9KDM4EMAPTHTT
	SCHEMBL2171543	0.81	VDR (0.52)	CYP1A2CYP2C9HTTALDH1A1MRGPRX4
	SCHEMBL4638408	0.81	CFTR (0.50)	KDM4EMAPTALDH1A1MEN1KMT2A
	SCHEMBL29617695	0.81	CFTR (0.50)	KDM4EMAPTALDH1A1MEN1KMT2A
	SCHEMBL477870	0.80	SLC6A9 (0.52)	KDM4EHTTALDH1A1KMT2AMAPK1
	SCHEMBL3441526	0.79	HTT (0.54)	CYP1A2CYP2C9KDM4EMAPTHTT
	SCHEMBL17180898	0.78	PTGDR2 (0.41)	CYP1A2CYP2C9KDM4EMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.