Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586127 | 0.92 | RAB9A (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8352681 | 0.84 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL28410803 | 0.82 | CYP3A4 (0.75) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL31067625 | 0.81 | MTOR (0.53) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL17064829 | 0.81 | MTOR (0.53) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL3216739 | 0.80 | ALDH1A1 (0.57) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL27500645 | 0.80 | MTOR (0.68) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8095249 | 0.79 | MTOR (1.00) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL5094749 | 0.78 | MTOR (0.65) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL18812586 | 0.78 | TDP1 (0.57) | MTORRAB9AGRM7CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951800-A1 | WEATHER-RESISTANT EPOXY RESIN SYSTEM | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007060077-A1 | WEATHER-RESISTANT EPOXY RESIN SYSTEM | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2007-05-31 | — | — | WO | disclosed |