SCHEMBL4640205

SCHEMBL4640205

CC(C)C1CCC(C)C(O)C1C

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.45
TRPM8 Q7Z2W7 2/20 0.45
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11302025 0.83 TRPA1 (0.46) TRPA1TRPM8EPHX1
SCHEMBL112754 0.83 TRPA1 (0.46) TRPA1TRPM8EPHX1
SCHEMBL11304709 0.83 TRPA1 (0.46) TRPA1TRPM8EPHX1
SCHEMBL15462830 0.83 TRPA1 (0.46) TRPA1TRPM8EPHX1
SCHEMBL15454324 0.83 TRPA1 (0.46) TRPA1TRPM8EPHX1
SCHEMBL25365753 0.81 TRPA1 (0.45) TRPA1TRPM8EPHX1
SCHEMBL12166525 0.81 TRPA1 (0.45) TRPA1TRPM8EPHX1
SCHEMBL5776136 0.79 TRPA1 (0.41) TRPA1TRPM8EPHX1
SCHEMBL12166664 0.79 KDM4E (0.33) TRPA1TRPM8
SCHEMBL25907749 0.75 TRPA1 (0.54) TRPA1TRPM8EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 EP disclosed
EP-1417896-B1 Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same INT FLAVORS & FRAGRANCES INC (US) 2008-08-13 EP disclosed