Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminocaproic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.58 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.58 |
| ▸ | GABRP | O00591 | 1/20 | 0.58 |
| ▸ | GABRD | O14764 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminocaproic Acid SCHEMBL4640369 | 0.96 | LMNA (0.74) | LMNAKMT2AALDH1A1THRBMEN1 | |
| 12-Aminododecanoic Acid SCHEMBL11153103 | 0.91 | LMNA (0.81) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Aminocaproic Acid SCHEMBL28868208 | 0.91 | LMNA (0.81) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Sulfuric Acid SCHEMBL9252702 | 0.91 | LMNA (0.81) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Aminocaproic Acid SCHEMBL28660274 | 0.89 | LMNA (0.94) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL9251424 | 0.87 | LMNA (0.74) | LMNAKMT2AALDH1A1THRBMEN1 | |
| 12-Aminododecanoic Acid SCHEMBL9255216 | 0.87 | LMNA (0.74) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Adipic Acid SCHEMBL11332689 | 0.86 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Pimelic Acid SCHEMBL21465298 | 0.86 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Sebacic Acid SCHEMBL9501168 | 0.86 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287558-A1 | Method of the Preparation of Vulcanization Mixtures by the De-Vulcanization of Waste Rubber | PROPS, S.R.O. (CZ) | 2008-11-20 | — | — | US | disclosed |
| EP-1954751-A2 | METHOD OF THE PREPARATION OF VULCANIZATION MIXTURES BY THE DE-VULCANIZATION OF WASTE RUBBER | Props, s.r.o. (CZ) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007062611-A2 | METHOD OF THE PREPARATION OF VULCANIZATION MIXTURES BY THE DE-VULCANIZATION OF WASTE RUBBER | PROPS, S.R.O. (CZ) | 2007-06-07 | — | — | WO | disclosed |