Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of 12-Aminododecanoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.74 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.74 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | PLG | P00747 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.58 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.58 |
| ▸ | GABRP | O00591 | 1/20 | 0.58 |
| ▸ | GABRD | O14764 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251424 | 1.00 | LMNA (0.74) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Aminocaproic Acid SCHEMBL28868208 | 0.91 | LMNA (0.81) | LMNAKMT2AALDH1A1THRBMEN1 | |
| 12-Aminododecanoic Acid SCHEMBL11153103 | 0.91 | LMNA (0.81) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Sulfuric Acid SCHEMBL9252702 | 0.91 | LMNA (0.81) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL28965375 | 0.89 | TSHR (0.67) | LMNAKMT2AALDH1A1MEN1ALOX15 | |
| Pimelic Acid SCHEMBL15353467 | 0.89 | TSHR (0.67) | LMNAKMT2AALDH1A1MEN1ALOX15 | |
| Aminocaproic Acid SCHEMBL4640369 | 0.87 | LMNA (0.74) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL2231728 | 0.86 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Pimelic Acid SCHEMBL21465298 | 0.86 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Adipic Acid SCHEMBL11332689 | 0.86 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5423998-A | Bleaching agent for detergent | AUSIMONT S.R.L. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5294362-A | Bleach | AUSIMONT S.R.L. (IT) | 1994-03-15 | — | — | US | disclosed |
| EP-0316809-B1 | Salts of amino-(poly)percarboxylic acids | AUSIMONT SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5245075-A | Bleaching agents | AUSIMONT S.R.L. (IT) | 1993-09-14 | — | — | US | disclosed |
| EP-0316809-A2 | Salts of amino-(poly)percarboxylic acids | AUSIMONT S.p.A. (IT) | 1989-05-24 | — | — | EP | disclosed |