SCHEMBL4640425

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14099345	0.91	KDM4E (0.42)	PARP1ERN1KDM4EALDH1A1HSD17B10
	SCHEMBL4640440	0.89	PARP1 (0.41)	PARP1ERN1KDM4EALDH1A1HSD17B10
	SCHEMBL4640372	0.87	JAK2 (0.46)	PARP1ERN1KDM4EALDH1A1HSD17B10
	SCHEMBL4642112	0.85	KDM4E (0.46)	PARP1ERN1KDM4EALDH1A1HSD17B10
	SCHEMBL4640351	0.84	ALDH1A1 (0.49)	ERN1KDM4EALDH1A1HSD17B10MAPK1
	SCHEMBL4740085	0.81	PARP1 (0.50)	PARP1ERN1SMN1; SMN2XDHSLC22A12
	SCHEMBL3945829	0.78	KDM4E (0.45)	ERN1KDM4EALDH1A1HSD17B10MAPK1
	SCHEMBL4739429	0.78	SMN1; SMN2 (0.50)	PARP1KDM4EALDH1A1MAPK1RAB9A
	SCHEMBL4733776	0.76	PARP1 (0.52)	PARP1ERN1KDM4EALDH1A1HSD17B10
	SCHEMBL4733991	0.76	MAP4K4 (0.39)	PARP1ERN1KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.