Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.39 |
| ▸ | TUBB | P07437 | 6/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640449 | 0.80 | RAB9A (0.58) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6787352 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4640436 | 0.72 | NR1H4 (0.54) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4640409 | 0.67 | LMNA (0.59) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9559881 | 0.67 | LMNA (0.46) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL4640519 | 0.65 | LMNA (0.52) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL6540579 | 0.65 | CA1 (0.53) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3216968 | 0.64 | TPMT (0.50) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28259429 | 0.64 | FYN (0.67) | FYNTSHR | |
| SCHEMBL12780302 | 0.64 | RAB9A (0.49) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297283-B1 | EXCELLENT INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY AND ARE HENCE USEFUL AS ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2001-10-02 | — | — | US | claimed |
| EP-0934924-B1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6576642-B2 | Inhibitors of the production of Ig E antibodies, antiallergens | KOWA CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20010039279-A1 | Diamide compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2001-11-08 | — | — | US | disclosed |
| US-6297283-B1 | EXCELLENT INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY AND ARE HENCE USEFUL AS ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-0934924-A1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039279-A1 | Diamide compounds and compositions containing the same | HRH4, HRH2, HRH1 | FYN 1623/4885RELA 1984/4885TUBB4A 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.