SCHEMBL4640674

SCHEMBL4640674

Nc1cc(N)nc(NC=O)n1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 1/20 0.32
BLM P54132 1/20 0.32
ALDH1A1 P00352 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4087492 0.76 ALDH1A1 (0.35) ALDH1A1
SCHEMBL14543886 0.75 CA12 (0.31)
SCHEMBL10905067 0.75 CA1 (0.34)
SCHEMBL19401 0.75 CA1 (0.34)
SCHEMBL18891261 0.74 SCN9A (0.46) MAPT
Water SCHEMBL9507408 0.73 CA1 (0.33)
Hydroxyamine SCHEMBL11315924 0.71 CA1 (0.32)
SCHEMBL11853374 0.71 S1PR2 (0.35) ALDH1A1
SCHEMBL10996792 0.71 ALDH1A1 (0.49) MAPTALDH1A1
Formaldehyde SCHEMBL3043572 0.71 CA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3359575-B1 ANTIBODIES SPECIFIC FOR 4,6-DIAMINO-5-(FORMYLAMINO) PYRIMIDINE AND USES THEREOF UNIV FLORIDA STATE RES FOUND (US) 2020-07-22 EP disclosed
US-10562978-B2 Methods using antibodies specific for 4,6-diamino-5-(formamido)pyrimidine FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-02-18 US disclosed
US-20180066071-A1 METHODS USING ANTIBODIES SPECIFIC FOR 4,6-DIAMINO-5-(FORMAMIDO)PYRIMIDINE UNIV FLORIDA STATE RES FOUND (US) 2018-03-08 US disclosed
US-9884920-B2 Antibodies specific for 4,6-diamino-5-(formamido)pyrimidine and uses thereof FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2018-02-06 US disclosed
US-20170101481-A1 ANTIBODIES SPECIFIC FOR 4,6-DIAMINO-5-(FORMYLAMINO)PYRIMIDINE AND USES THEREOF FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2017-04-13 US disclosed
WO-2017062966-A1 ANTIBODIES SPECIFIC FOR 4,6-DIAMINO-5-(FORMYULAMINO) PYRIMIDINE AND USES THEREOF FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2017-04-13 WO disclosed
EP-1957057-A1 STRUCTURAL CAROTENOID ANALOGS OR DERIVATIVES FOR THE MODULATION OF SYSTEMIC AND/OR TARGET ORGAN REDOX STATUS Cardax Pharmaceuticals, Inc. (US) 2008-08-20 EP disclosed
US-20070238793-A1 Structural carotenoid analogs or derivatives for the modulation of systemic and/or target organ redox status CARDAX PHARMACEUTICALS, INC. 2007-10-11 US disclosed
WO-2007067957-A1 STRUCTURAL CAROTENOID ANALOGS OR DERIVATIVES FOR THE MODULATION OF SYSTEMIC AND/OR TARGET ORGAN REDOX STATUS CARDAX PHARMACEUTICALS, INC. (US) 2007-06-14 WO disclosed
US-20050215529-A1 Method of treating oxidative stress-associated conditions with isopentenyl diphosphate THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238793-A1 Structural carotenoid analogs or derivatives for the modulation of systemic and/or target organ redox status LPO, TXN2, TXNRD2 MAPT 3121/4885TDP1 1541/4885CYP3A4 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.