Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640703 | 0.95 | ALDH1A1 (0.38) | ALDH1A1MAPK1TSHRCTSKMEN1 | |
| SCHEMBL4641177 | 0.92 | ALDH1A1 (0.36) | ALDH1A1MAPK1TSHRCTSKESR1 | |
| SCHEMBL4640233 | 0.90 | ALDH1A1 (0.37) | ALDH1A1MAPK1TSHRCTSKPRKCA | |
| SCHEMBL4640612 | 0.87 | UTS2R (0.36) | ALDH1A1MAPK1TSHRCTSKESR1 | |
| SCHEMBL4641181 | 0.87 | MEN1 (0.42) | ALDH1A1MAPK1TSHRCTSKESR1 | |
| SCHEMBL4640671 | 0.86 | GRIN2D (0.32) | UTS2RMEN1KMT2A | |
| SCHEMBL4640235 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPK1TSHRCTSKPRKCA | |
| SCHEMBL4640432 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MAPK1TSHRCTSKESR1 | |
| SCHEMBL4640928 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MAPK1TSHRCTSKESR1 | |
| SCHEMBL4641263 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1TSHRCTSKESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188739-B1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6670497-B2 | Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst | TOHO TITANIUM CO., LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | TOHO TITANIUM CO., LTD. (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1188739-A1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO., LTD. (JP) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | HPD, ETFA, PPOX | ALDH1A1 725/4885MAPK1 921/4885TSHR 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.