SCHEMBL4640728

SCHEMBL4640728

Cc1ccc(C(=O)OC(C(C)(C)C)C(C)(C)C)c(C(=O)OC(C(C)(C)C)C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CSNK2A1 P68400 1/20 0.38
UTS2R Q9UKP6 1/20 0.36
CYP46A1 Q9Y6A2 1/20 0.36
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
HDAC7 Q8WUI4 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4640734 0.92 CSNK2A1 (0.46) KDM4EALDH1A1MAPTPKMCA12
SCHEMBL5611240 0.82 TDP1 (0.36) MAPTCA12CA1CA2CA7
SCHEMBL15675408 0.82 CA12 (0.58) KDM4EALDH1A1MAPTPKMCA12
SCHEMBL4641290 0.81 ALDH1A1 (0.38) KDM4EALDH1A1MAPTPKMCA12
SCHEMBL4640100 0.80 AKR1C3 (0.39) KDM4EALDH1A1MAPTCA12CA1
SCHEMBL4639947 0.80 TSHR (0.46) KDM4EALDH1A1MAPTCA1CA2
SCHEMBL6351061 0.77 CSNK2A1 (0.41) CSNK2A1CYP46A1HDAC7NPC1RAB9A
SCHEMBL4640109 0.76 ALDH1A1 (0.42) KDM4EALDH1A1MAPTPKMCA2
SCHEMBL5611244 0.76 KDM4E (0.36) KDM4EALDH1A1UTS2R
SCHEMBL29400811 0.76 KDM4E (0.36) KDM4EALDH1A1UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645625-B1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-27 EP disclosed
US-11732067-B2 High stiffness polypropylene impact copolymer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
CN-110997795-B High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2022-10-04 CN disclosed
CN-110799549-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2022-03-15 CN disclosed
US-20200140584-A1 High Stiffness Polypropylene Impact Copolymer EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-05-07 US disclosed
EP-3645586-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND A PROCESS FOR PROPYLENE POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2020-05-06 EP disclosed
EP-3645625-A1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER ExxonMobil Chemical Patents Inc. (US) 2020-05-06 EP disclosed
CN-110997795-A High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2020-04-10 CN disclosed
CN-110799549-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2020-02-14 CN disclosed
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX KDM4E 4127/4885ALDH1A1 725/4885MAPT 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.