Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.74 |
| ▸ | CA2 | P00918 | 5/20 | 0.74 |
| ▸ | CA9 | Q16790 | 5/20 | 0.74 |
| ▸ | CA1 | P00915 | 4/20 | 0.74 |
| ▸ | CA6 | P23280 | 3/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA5A | P35218 | 2/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.64 |
| ▸ | CA4 | P22748 | 2/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | TYR | P14679 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27164912 | 1.00 | CA12 (0.74) | CA12CA2CA9CA1CA6 | |
| Paraben SCHEMBL565120 | 0.95 | CA12 (0.73) | CA12CA2CA9CA1CA6 | |
| Terephthalic Acid SCHEMBL904446 | 0.93 | CA12 (0.79) | CA12CA2CA9CA1CA6 | |
| Terephthalic Acid SCHEMBL28483540 | 0.93 | CA12 (0.79) | CA12CA2CA9CA1CA6 | |
| Terephthalic Acid SCHEMBL28651640 | 0.93 | CA12 (0.79) | CA12CA2CA9CA1CA6 | |
| Benzoic Acid SCHEMBL5974437 | 0.93 | CA12 (0.78) | CA12CA2CA9CA1CA6 | |
| Benzoic Acid SCHEMBL124054 | 0.93 | CA12 (0.78) | CA12CA2CA9CA1CA6 | |
| 4-Methylbenzoic Acid SCHEMBL28007993 | 0.89 | ALDH1A1 (0.68) | CA12CA2CA9CA1CA6 | |
| 3-Hydroxybenzoic Acid SCHEMBL18393380 | 0.88 | CA12 (0.95) | CA12CA2CA9CA1CA6 | |
| Isophthalic Acid SCHEMBL3172446 | 0.88 | CA12 (0.86) | CA12CA2CA9CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583564-B | Composition, method of making the same, and articles made therefrom | High tech special engineering plastics Global Technology Co.,Ltd. (NL) | 2026-05-26 | — | — | CN | claimed |
| CN-119768458-A | Thermoplastic composition, method of making the same, and articles made therefrom | 高新特殊工程塑料全球技术有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-114207040-B | Thermoplastic composition and metallized article made therefrom | 高新特殊工程塑料全球技术有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-117321139-A | Weather resistant polyester carbonate copolymers for interior and exterior train components | 高新特殊工程塑料全球技术有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-116583564-A | Composition, method of making the same, and articles made therefrom | 高新特殊工程塑料全球技术有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-113439108-B | Compositions having improved chemical resistance, articles formed therefrom, and methods of manufacture | 高新特殊工程塑料全球技术有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-114207040-A | Thermoplastic composition and metallized articles made therefrom | 高新特殊工程塑料全球技术有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-101765638-A | Polyester polycarbonate compositions, methods of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP | 2010-06-30 | — | — | CN | claimed |
| CN-1262572-C | Weatherable block copolycarbonates and blends containing the same | GEN ELECTRIC (US) | 2006-07-05 | — | — | CN | claimed |
| EP-1124878-B1 | WEATHERABLE BLOCK COPOLYESTERCARBONATES AND BLENDS CONTAINING THEM | GEN ELECTRIC (US) | 2004-01-21 | — | — | EP | claimed |
| JP-2002528614-A | — | — | 2002-09-03 | — | — | JP | claimed |
| CN-1332760-A | Weatherable block copolycarbonates and blends containing the same | GEN ELECTRIC (US) | 2002-01-23 | — | — | CN | claimed |
| EP-1124878-A1 | WEATHERABLE BLOCK COPOLYESTERCARBONATES AND BLENDS CONTAINING THEM | GENERAL ELECTRIC COMPANY (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000026274-A1 | WEATHERABLE BLOCK COPOLYESTERCARBONATES AND BLENDS CONTAINING THEM | GENERAL ELECTRIC COMPANY (US) | 2000-05-11 | — | — | WO | claimed |
| CN-116583564-B | Composition, method of making the same, and articles made therefrom | High tech special engineering plastics Global Technology Co.,Ltd. (NL) | 2026-05-26 | — | — | CN | disclosed |
| WO-2026041597-A2 | METHOD FOR RECYCLING AROMATIC POLYCARBONATE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2026-02-26 | — | — | WO | disclosed |
| WO-2026041598-A2 | METHOD FOR RECYCLING AROMATIC POLYCARBONATE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2026-02-26 | — | — | WO | disclosed |
| EP-1171513-A1 | WEATHERABLE MULTILAYER RESINOUS ARTICLES AND METHOD FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| US-20010055671-A1 | Weatherable multilayer articles and method for their preparation | GENERAL ELECTRIC COMPANY | 2001-12-27 | — | — | US | disclosed |
| WO-2000061664-A1 | WEATHERABLE MULTILAYER RESINOUS ARTICLES AND METHOD FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2000-10-19 | — | — | WO | disclosed |