Terephthalic Acid

Terephthalic Acid

SCHEMBL904446

O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1cccc(C(=O)O)c1.Oc1cccc(O)c1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.79
CA2 P00918 5/20 0.79
CA9 Q16790 5/20 0.79
CA1 P00915 4/20 0.79
CA6 P23280 3/20 0.79
CA14 Q9ULX7 4/20 0.56
CA7 P43166 3/20 0.56
CA5A P35218 2/20 0.56
CA5B Q9Y2D0 2/20 0.56
CA4 P22748 2/20 0.56
CA3 P07451 1/20 0.56
TYR P14679 1/20 0.56
DRD1 P21728 1/20 0.56
TSHR P16473 2/20 0.54
DAO P14920 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
P4HB P07237 1/20 0.53
HSD17B10 Q99714 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28483540 1.00 CA12 (0.79) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL28651640 1.00 CA12 (0.79) CA12CA2CA9CA1CA6
Isophthalic Acid SCHEMBL28353233 0.96 CA12 (0.86) CA12CA2CA9CA1CA6
Isophthalic Acid SCHEMBL3172446 0.96 CA12 (0.86) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL27164912 0.93 CA12 (0.74) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL4640732 0.93 CA12 (0.74) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL28317800 0.91 CA12 (0.72) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL440232 0.91 CA12 (0.72) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL9634104 0.91 CA12 (0.72) CA12CA2CA9CA1CA6
Terephthalic Acid SCHEMBL5494023 0.91 CA12 (0.72) CA12CA2CA9CA1CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132588-A1 A POLYCARBONATE COMPOSITION WITH IMPROVED FLAME PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-06-27 WO claimed
EP-4389824-A1 A POLYCARBONATE COMPOSITION WITH IMPROVED FLAME PROPERTIES SABIC Global Technologies B.V. (NL) 2024-06-26 EP claimed
EP-3941977-B1 HIGH STIFF THERMOPLASTIC COMPOSITIONS FOR THIN-WALL STRUCTURES SHPP GLOBAL TECH BV (NL) 2024-05-01 EP claimed
US-20240076490-A1 Transparent Weatherable Electrically Conductive Polycarbonate Blend Compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-03-07 US claimed
WO-2023233325-A1 THERMOPLASTIC COMPOSITIONS HAVING HIGH METAL BONDING FORCE FOR NMT APPLICATIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-12-07 WO claimed
EP-4286479-A1 THERMOPLASTIC COMPOSITIONS HAVING HIGH METAL BONDING FORCE FOR NMT APPLICATIONS SHPP Global Technologies B.V. (NL) 2023-12-06 EP claimed
EP-4271753-A1 TRANSPARENT WEATHERABLE ELECTRICALLY CONDUCTIVE POLYCARBONATE BLEND COMPOSITIONS SHPP Global Technologies B.V. (NL) 2023-11-08 EP claimed
CN-114026172-B High rigidity thermoplastic composition for thin wall structures 高新特殊工程塑料全球技术有限公司 2023-10-31 CN claimed
CN-116867853-A Transparent weather-resistant conductive polycarbonate blend composition 高新特殊工程塑料全球技术有限公司 2023-10-10 CN claimed
WO-2023131902-A1 THERMOPLASTIC COMPOSITIONS WITH IMPROVED PERFORMANCE FOR NANO MOLDING TECHNOLOGY (NMT) SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-07-13 WO claimed
US-20060018123-A1 Curing light having a reflector DISCUS DENTAL, LLC 2006-01-26 US claimed
US-20030207096-A1 Weatherable multilayer resinous articles and method for their prepartion SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-11-06 US claimed
US-6572956-B1 Protective coating of such as resorcinol, isophthalic acid and terephthalic acid copolyester; photoyellowing resistance; gloss retention; solvent resistance; recyclability GENERAL ELECTRIC COMPANY 2003-06-03 US claimed
EP-1115792-B1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GEN ELECTRIC (US) 2003-04-23 EP claimed
JP-2002542325-A 2002-12-10 JP claimed
EP-1171513-A1 WEATHERABLE MULTILAYER RESINOUS ARTICLES AND METHOD FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2002-01-16 EP claimed
EP-1115792-A1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GENERAL ELECTRIC COMPANY (US) 2001-07-18 EP claimed
US-6143839-A THERMOPLASTIC ARYLATE POLYMER COMPRISING UNITS DERIVED FROM A RESORCINOL OR ALKYLRESORCINOL ISOPHTHALATE-TEREPHTHALATE IMPROVES COLOR STABILITY OR GLOSS RETENTION OF THE POLYCARBONATE; ARTICLES MADE FROM THE BLEND GENERAL ELECTRIC COMPANY (US) 2000-11-07 US claimed
WO-2000061664-A1 WEATHERABLE MULTILAYER RESINOUS ARTICLES AND METHOD FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2000-10-19 WO claimed
WO-2000015718-A1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GENERAL ELECTRIC COMPANY (US) 2000-03-23 WO claimed