Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831035 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TP53CLCN2TSHRPOLB | |
| SCHEMBL19554797 | 0.84 | GABRP (0.46) | ALDH1A1TP53POLBLMNAGABRP | |
| SCHEMBL21351963 | 0.84 | TSHR (0.50) | ALDH1A1TP53CLCN2TSHRLMNA | |
| SCHEMBL4116012 | 0.84 | GABRP (0.50) | ALDH1A1CLCN2TSHRGABRPGABRD | |
| SCHEMBL29077090 | 0.83 | GABRP (0.50) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13244501 | 0.83 | GABRP (0.47) | ALDH1A1TP53CLCN2TSHRPOLB | |
| Ethane SCHEMBL4640849 | 0.82 | MEN1 (0.35) | ALDH1A1TP53CLCN2TSHRPOLB | |
| SCHEMBL8189899 | 0.81 | KDM4E (0.49) | ALDH1A1TSHRSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL13180375 | 0.80 | KEAP1 (0.42) | ALDH1A1TP53CLCN2TSHRPOLB | |
| SCHEMBL4641133 | 0.79 | MEN1 (0.36) | ALDH1A1TP53CLCN2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188739-B1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |