Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 9/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641950 | 0.89 | FPR2 (0.40) | FPR2POLBTDP1 | |
| SCHEMBL5597243 | 0.78 | HSD17B3 (0.46) | FPR2HSD17B3 | |
| SCHEMBL4642325 | 0.77 | HSD17B3 (0.47) | HSD17B3 | |
| SCHEMBL5597129 | 0.74 | FPR2 (0.41) | FPR2 | |
| SCHEMBL4642757 | 0.74 | HSD17B3 (0.44) | FPR2HSD17B3 | |
| SCHEMBL4640750 | 0.73 | TBXAS1 (0.50) | POLBTDP1FAAHDAGLATBXAS1 | |
| SCHEMBL8088802 | 0.70 | FPR2 (0.43) | FPR2 | |
| SCHEMBL4640751 | 0.69 | L3MBTL1 (0.42) | FPR2HSD17B3 | |
| SCHEMBL2351291 | 0.69 | CYP17A1 (0.43) | TBXAS1 | |
| SCHEMBL14880753 | 0.69 | CYP1A2 (0.42) | FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804805-A4 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | UNIV WAYNE STATE (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1804805-A2 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | WAYNE STATE UNIVERSITY (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006041941-A2 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | WAYNE STATE UNIVERSITY (US) | 2006-04-20 | — | — | WO | disclosed |
| EP-1492515-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AROMATASE INHIBITOR AND AN ESTROGEN SUITABLE FOR HORMONE REPLACEMENT THERAPY FOR A MALE | JENCAP RESEARCH LTD. (CA) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082254-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AROMATASE INHIBITOR AND AN ESTROGEN SUITABLE FOR HORMONE REPLACEMENT THERAPY FOR A MALE | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |
| WO-2003082299-A1 | IMPROVED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |