Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146293 | 0.75 | — | — | |
| SCHEMBL82068 | 0.73 | — | — | |
| SCHEMBL25933296 | 0.73 | — | — | |
| SCHEMBL2879345 | 0.73 | TSHR (0.52) | LMNAALDH1A1POLB | |
| SCHEMBL442562 | 0.71 | — | — | |
| SCHEMBL28340352 | 0.71 | — | — | |
| SCHEMBL19300404 | 0.71 | — | — | |
| SCHEMBL3660629 | 0.71 | LMNA (0.63) | LMNAALDH1A1MCL1POLB | |
| SCHEMBL775285 | 0.70 | — | — | |
| SCHEMBL8015405 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869032-B1 | PYRIMIDINE DERIVATIVES FOR USE AS ANTICANCER AGENTS | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | EP | disclosed |