Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641001 | 0.77 | MAPT (0.58) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL7099910 | 0.77 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL4345971 | 0.76 | PIK3CA (0.71) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL20745310 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL4348304 | 0.74 | PIK3CA (0.58) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4348336 | 0.73 | PIK3CA (0.50) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4640142 | 0.71 | BRAF (0.64) | PDGFRBPDGFRAEGFRMEN1KMT2A | |
| SCHEMBL14098756 | 0.71 | NPC1 (0.65) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL30081003 | 0.71 | KMT2A (0.70) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL28894335 | 0.71 | KMT2A (0.70) | KDM4EALDH1A1HPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267819-B1 | Quinoxaline derivatives, compositions containing them und use as UV-filter | MERCK PATENT GMBH (DE) | 2008-08-06 | — | — | EP | claimed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | claimed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | PDGFRB 4344/4885PDGFRA 4218/4885KDM4E 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.