⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401727 | 0.81 | KDM6B (0.43) | — | |
| SCHEMBL11517514 | 0.78 | — | — | |
| SCHEMBL964192 | 0.75 | — | — | |
| SCHEMBL29180353 | 0.72 | — | — | |
| Chloromethane SCHEMBL28663449 | 0.70 | ALDH1A1 (0.46) | — | |
| Chloromethane SCHEMBL10408053 | 0.69 | KDM6B (0.32) | — | |
| Chloromethane SCHEMBL10408050 | 0.69 | KDM6B (0.32) | — | |
| SCHEMBL545157 | 0.69 | — | — | |
| SCHEMBL4018720 | 0.67 | KDM6B (0.43) | — | |
| SCHEMBL25410111 | 0.67 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957059-A1 | ANDROGEN-RECEPTOR (AR) LIGANDS FOR USE IN THE TREATMENT AND DIAGNOSIS OF AR-RELATED PATHOLOGIES | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007057909-A1 | ANDROGEN-RECEPTOR (AR) LIGANDS FOR USE IN THE TREATMENT AND DIAGNOSIS OF AR-RELATED PATHOLOGIES | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. (IL) | 2007-05-24 | — | — | WO | disclosed |