SCHEMBL4641913

SCHEMBL4641913

CC(=O)C(=O)C(Cl)Oc1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
PPARG P37231 2/20 0.41
PPARA Q07869 2/20 0.41
MAOB P27338 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MAPT P10636 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 2/20 0.35
ALOX15 P16050 1/20 0.35
GFER P55789 1/20 0.35
ADAM17 P78536 1/20 0.35
MAOA P21397 1/20 0.35
TP53 P04637 2/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643658 0.81 MTNR1A (0.45) ALDH1A1PPARGPPARASMN1; SMN2MAPT
SCHEMBL4643815 0.80 ALDH1A1 (0.47) ALDH1A1PPARGPPARAMAOBSMN1; SMN2
SCHEMBL9721990 0.79 PPARG (0.51) ALDH1A1PPARGPPARASMN1; SMN2MAPT
SCHEMBL27851337 0.79 ALDH1A1 (0.46) ALDH1A1PPARGPPARAMAOBSMN1; SMN2
SCHEMBL4642044 0.72 HDAC3 (0.41) ALDH1A1SMN1; SMN2MAPTLMNAPOLB
SCHEMBL6617425 0.72 ALDH1A1 (0.64) ALDH1A1PPARGPPARASMN1; SMN2MAPT
SCHEMBL11209577 0.70 ALDH1A1 (0.62) ALDH1A1PPARGPPARASMN1; SMN2MAPT
SCHEMBL10343853 0.69 ALDH1A1 (0.41) ALDH1A1PPARGPPARA
SCHEMBL15156205 0.69 ALDH1A1 (0.47) ALDH1A1PPARGPPARAMAOBSMN1; SMN2
SCHEMBL9818914 0.68 CYP1A2 (0.65) ALDH1A1PPARGPPARASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed