SCHEMBL4641933

SCHEMBL4641933

CC(C)[SiH](OC(=O)CCCCCl)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.31
DGKA P23743 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642473 0.94 LMNA (0.33) LMNAMAPTTSHR
SCHEMBL4645531 0.86
SCHEMBL4646814 0.82 LMNA (0.37) LMNAMAPTTSHRMAPK1DGKA
SCHEMBL27619973 0.81 ALDH1A1 (0.40) LMNAMAPTTSHR
SCHEMBL4644680 0.78 LMNA (0.33) LMNAMAPTTSHR
SCHEMBL4643905 0.77 FAAH (0.30) FAAH
SCHEMBL4647651 0.75 CA1 (0.30)
SCHEMBL7761299 0.75 ALDH1A1 (0.48) LMNAMAPTTSHRMAPK1DGKA
SCHEMBL21811931 0.74 MAPT (0.50) LMNAMAPTTSHRDGKA
SCHEMBL1364866 0.74 LMNA (0.64) LMNAMAPTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed