Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4641948

O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccc(Sc3ccc([I+]c4ccc(Sc5ccc([S+](c6ccccc6)c6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.36
MMP13 P45452 3/20 0.32
MMP8 P22894 2/20 0.32
MMP3 P08254 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
MMP2 P08253 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL4641439 0.99 GPR3 (0.35) GPR3MMP13MMP8MMP3ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL29767233 0.90 GPR3 (0.40) GPR3MMP13MMP8MMP3ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL51462 0.90 GPR3 (0.40) GPR3MMP13MMP8MMP3ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL4644731 0.88 KCNH2 (0.30) GPR3
Trifluoromethanesulfonic Acid SCHEMBL4643958 0.88 MLYCD (0.37) GPR3ALDH1A1HPGD
SCHEMBL4641435 0.87 CA1 (0.30) MMP13MMP8MMP2
Trifluoromethanesulfonic Acid SCHEMBL4643720 0.87 GPR3 (0.38) GPR3PTPN1
SCHEMBL4644645 0.86
Trifluoromethanesulfonic Acid SCHEMBL4643615 0.86 MMP1 (0.36) GPR3MMP13
Trifluoromethanesulfonic Acid SCHEMBL4641619 0.85 KCNH2 (0.30) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP claimed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US claimed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US claimed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP claimed
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed