SCHEMBL4641966

SCHEMBL4641966

CC[CH]C(=O)Oc1ccccc1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
NFE2L2 Q16236 2/20 0.44
KMT2A Q03164 2/20 0.43
ATM Q13315 1/20 0.43
MEN1 O00255 1/20 0.43
PLIN1 O60240 1/20 0.43
PLIN5 Q00G26 1/20 0.43
ABHD5 Q8WTS1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646795 0.86 POLB (0.45) POLBSMN1; SMN2CA12CA1CA2
SCHEMBL4642500 0.82 GAA (0.46) POLBSMN1; SMN2CA12CA1CA2
SCHEMBL9284213 0.81 MAPT (0.58) POLBSMN1; SMN2CA12CA1CA2
SCHEMBL4647755 0.81 ALDH1A1 (0.52) POLBSMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL4644835 0.80 CA12 (0.52) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL4644831 0.80 SLC6A3 (0.58) POLBMAPTALDH1A1LMNAL3MBTL1
SCHEMBL28477536 0.79 CA1 (0.52) POLBSMN1; SMN2CA12CA1CA2
SCHEMBL4644181 0.79 CA1 (0.52) POLBSMN1; SMN2CA12CA1CA2
SCHEMBL31538165 0.79 CA1 (0.52) POLBSMN1; SMN2CA12CA1CA2
SCHEMBL2235806 0.78 THRA (0.53) POLBSMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed