SCHEMBL4642000

SCHEMBL4642000

CCCCCC[Si](CCCCCC)(CCCCCC)OC(=O)CCCO

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.44
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
LMNA P02545 5/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PAM P19021 2/20 0.41
NAAA Q02083 1/20 0.41
KDM4E B2RXH2 1/20 0.40
DUSP3 P51452 1/20 0.40
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647907 1.00 DGKA (0.44) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4643700 0.98 DGKA (0.41) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4641981 0.95 DGKA (0.47) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4644552 0.95 DGKA (0.47) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4643819 0.93 DGKA (0.44) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4644612 0.93 DGKA (0.38) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4644579 0.91 NAAA (0.46) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4644657 0.91 NAAA (0.46) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL6545816 0.89 DGKA (0.47) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4643224 0.89 NAAA (0.43) DGKAMAPTMAPK1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed