SCHEMBL4643700

SCHEMBL4643700

CCCCC[Si](CCCCC)(CCCCC)OC(=O)CCCO

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 5/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 1/20 0.38
PAM P19021 2/20 0.38
NAAA Q02083 1/20 0.38
KDM4E B2RXH2 1/20 0.38
DUSP3 P51452 1/20 0.38
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642000 0.98 DGKA (0.44) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4647907 0.98 DGKA (0.44) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4643819 0.95 DGKA (0.44) DGKAMAPTMAPK1SMN1; SMN2LMNA
SCHEMBL4644612 0.94 DGKA (0.38) DGKAMAPTMAPK1SMN1; SMN2LMNA
SCHEMBL4644552 0.93 DGKA (0.47) DGKAMAPTMAPK1SMN1; SMN2LMNA
SCHEMBL4641981 0.93 DGKA (0.47) DGKAMAPTMAPK1SMN1; SMN2LMNA
SCHEMBL4643224 0.91 NAAA (0.43) DGKAMAPTMAPK1SMN1; SMN2LMNA
SCHEMBL4643596 0.89 DGKA (0.41) DGKAMAPTMAPK1SMN1; SMN2LMNA
SCHEMBL4644579 0.89 NAAA (0.46) DGKAMAPTMAPK1LMNAMEN1
SCHEMBL4644657 0.89 NAAA (0.46) DGKAMAPTMAPK1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed