SCHEMBL4642010

SCHEMBL4642010

CC(C)(C)[Si](OC(=O)CCCCl)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
PPARA Q07869 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RAB9A P51151 1/20 0.32
LTB4R Q15722 1/20 0.32
LMNA P02545 1/20 0.31
TOP2A P11388 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641886 0.96 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL4644075 0.91 HIF1A (0.32) ALDH1A1MAPTPPARA
SCHEMBL6545076 0.91 KDM4E (0.36) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL6546547 0.88 CYP2C19 (0.35) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL27601469 0.87 HPGD (0.34) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL6663589 0.87 TSHR (0.41) ALDH1A1SMN1; SMN2MAPT
SCHEMBL4641522 0.87 KDM4E (0.34) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL30116362 0.87 KDM4E (0.46) ALDH1A1MEN1KMT2AKDM4ERECQL
SCHEMBL4647018 0.85 PRSS1 (0.34) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL3176375 0.85 HDAC3 (0.42) ALDH1A1SMN1; SMN2MAPTPPARALTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed