SCHEMBL4644075

SCHEMBL4644075

CC(C)(C)[Si](OC(=O)CCCl)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.32
CYP2C19 P33261 1/20 0.32
ABL1 P00519 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 2/20 0.31
TRPA1 O75762 1/20 0.31
MAPK1 P28482 1/20 0.31
GSK3B P49841 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642010 0.91 ALDH1A1 (0.35) MAPTALDH1A1PPARA
SCHEMBL6546547 0.90 CYP2C19 (0.35) HIF1ACYP2C19ABL1MAPTTDP1
SCHEMBL4641886 0.90 SMN1; SMN2 (0.35) ALDH1A1
SCHEMBL4647641 0.87 ALDH1A1 (0.36) HIF1ACYP2C19ABL1MAPTTDP1
SCHEMBL6545076 0.87 KDM4E (0.36) HIF1ACYP2C19ABL1MAPTTDP1
SCHEMBL6656947 0.86 NR4A2 (0.38) HIF1ACYP2C19ALDH1A1MAPK1
SCHEMBL4644661 0.86 CYP2C19 (0.33) HIF1ACYP2C19ABL1MAPTTDP1
SCHEMBL4643575 0.84 CYP2C19 (0.32) HIF1ACYP2C19ABL1MAPTTDP1
SCHEMBL27601469 0.84 HPGD (0.34) ABL1ALDH1A1
SCHEMBL6072557 0.83 ABL1 (0.35) HIF1ACYP2C19ABL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed