SCHEMBL4642201

SCHEMBL4642201

C[CH]C(=O)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
ALOX15 P16050 4/20 0.37
ALOX12 P18054 4/20 0.37
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AKR1C4 P17516 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
AKR1C1 Q04828 1/20 0.34
ERN1 O75460 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TPMT P51580 1/20 0.33
GAA P10253 1/20 0.33
APOBEC3A P31941 1/20 0.33
HTT P42858 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643493 0.88 HSD17B10 (0.40) HSD17B10ALOX15ALOX12MAPTHPGD
SCHEMBL4644715 0.86 ERN1 (0.47) HSD17B10ALOX15ALOX12MAPTERN1
SCHEMBL4644362 0.81 POLB (0.40) HSD17B10MAPTTSHRCYP3A4MEN1
SCHEMBL316904 0.80 HSD17B10 (0.42) HSD17B10ALOX15ALOX12MAPTHPGD
SCHEMBL4647866 0.79 HSD17B10 (0.42) HSD17B10ALOX15ALOX12MAPTHPGD
SCHEMBL4647729 0.77 HSD17B10 (0.50) HSD17B10ALOX15ALOX12MAPTTSHR
SCHEMBL4644186 0.77 HSD17B10 (0.40) HSD17B10ALOX15ALOX12MAPTHPGD
SCHEMBL23855075 0.76 HSD17B10 (0.48) HSD17B10ALOX15ALOX12MAPTHPGD
SCHEMBL5704226 0.76 HSD17B10 (0.48) HSD17B10ALOX15ALOX12MAPTHPGD
SCHEMBL9670424 0.74 HSD17B10 (0.47) HSD17B10ALOX15ALOX12MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed