SCHEMBL4644186

SCHEMBL4644186

CCC[CH]C(=O)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
THRB P10828 6/20 0.36
THRA P10827 5/20 0.36
ALDH1A1 P00352 4/20 0.33
MAPT P10636 4/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
LMNA P02545 1/20 0.32
HPGD P15428 2/20 0.31
HTT P42858 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644078 0.90 HSD17B10 (0.36) HSD17B10THRBTHRAALDH1A1KMT2A
SCHEMBL4647606 0.88 ERN1 (0.41) HSD17B10THRBTHRAALDH1A1MAPT
SCHEMBL4647866 0.86 HSD17B10 (0.42) HSD17B10THRBTHRAALDH1A1MAPT
SCHEMBL4644487 0.84 POLB (0.36) THRBTHRAALDH1A1MAPTKMT2A
SCHEMBL4642201 0.77 HSD17B10 (0.46) HSD17B10THRBMAPTKMT2AGAA
SCHEMBL4642286 0.76 HSD17B10 (0.37) HSD17B10THRBTHRAALDH1A1KMT2A
SCHEMBL4646065 0.76 MGLL (0.49) THRBMAPTKMT2AMEN1LMNA
SCHEMBL4644807 0.75 ERN1 (0.44) HSD17B10THRBALDH1A1MAPTKMT2A
SCHEMBL3769997 0.74 GAA (0.32) THRBGAAPOLB
SCHEMBL4643660 0.73 KMT2A (0.34) THRBALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed