SCHEMBL4642255

SCHEMBL4642255

O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.c1ccc([I+]c2ccc(Cc3ccc([S+](c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.35
CA2 P00918 13/20 0.35
MMP1 P03956 4/20 0.34
MMP2 P08253 4/20 0.34
MMP9 P14780 4/20 0.34
MMP8 P22894 4/20 0.34
MMP13 P45452 4/20 0.34
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641390 0.99 CA1 (0.34) CA1CA2MMP1MMP2MMP9
SCHEMBL6023248 0.88 CA1 (0.31) CA1CA2MMP1MMP2MMP9
SCHEMBL4641444 0.88 CA1 (0.31) CA1CA2MMP1MMP2MMP9
SCHEMBL4641408 0.88 KCNH2 (0.35) CA1CA2
SCHEMBL4643440 0.88 PTPN1 (0.33) CA1CA2MMP1MMP2MMP9
Trifluoromethanesulfonic Acid SCHEMBL4643970 0.88 GPR3 (0.35) CA1CA2MMP13CA12CA9
Trifluoromethanesulfonic Acid SCHEMBL4641374 0.86 GPR3 (0.36) CA1CA2MMP13CA12CA9
SCHEMBL4643684 0.86 SOS1 (0.32)
SCHEMBL4644645 0.86
SCHEMBL4641411 0.86 CA1 (0.30) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed