Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4641374

O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccc(Cc3ccc([I+]c4ccc(Cc5ccc([S+](c6ccccc6)c6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.36
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
KCNH2 Q12809 1/20 0.33
LMNA P02545 1/20 0.31
PDPK1 O15530 1/20 0.31
PTPRZ1 P23471 1/20 0.31
MMP13 P45452 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL4643970 0.99 GPR3 (0.35) GPR3CA2CA12CA1CA9
Trifluoromethanesulfonic Acid SCHEMBL4643441 0.90 CA2 (0.42) GPR3CA2CA12CA1CA9
Trifluoromethanesulfonic Acid SCHEMBL4647330 0.88 KCNH2 (0.33) GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL4644616 0.88 KCNH2 (0.44) GPR3CA2CA1CA9KCNH2
SCHEMBL4641390 0.87 CA1 (0.34) CA2CA12CA1CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL4643720 0.87 GPR3 (0.38) GPR3CA2CA12CA1CA9
SCHEMBL4642255 0.86 CA1 (0.35) CA2CA12CA1CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL4641793 0.85 KCNH2 (0.33) GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL4644622 0.85 KCNH2 (0.34) GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL4643549 0.83 SOS1 (0.37) GPR3CA2CA1CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed