SCHEMBL4642260

SCHEMBL4642260

COC(=O)Cc1ccccc1OC(=O)CO

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.49
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ATM Q13315 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050491 0.88 KDM4E (0.53) L3MBTL1ALDH1A1MEN1KMT2ATDP1
SCHEMBL27619976 0.87 L3MBTL1 (0.47) L3MBTL1CYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL4644486 0.85 L3MBTL1 (0.48) L3MBTL1ALDH1A1MEN1KMT2ATDP1
SCHEMBL4641986 0.85 L3MBTL1 (0.48) L3MBTL1ALDH1A1MEN1KMT2ATDP1
SCHEMBL4646605 0.85 KDM4E (0.47) L3MBTL1ALDH1A1MEN1KMT2ATDP1
SCHEMBL4646741 0.84 L3MBTL1 (0.45) L3MBTL1CYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL4646600 0.83 L3MBTL1 (0.46) L3MBTL1ALDH1A1MEN1KMT2ATDP1
SCHEMBL4645857 0.83 L3MBTL1 (0.44) L3MBTL1CYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL27726150 0.83 L3MBTL1 (0.51) L3MBTL1CYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL4643555 0.83 L3MBTL1 (0.46) L3MBTL1ALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed