SCHEMBL4641986

SCHEMBL4641986

[CH2]CC(=O)Oc1ccccc1CC(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.48
KDM4E B2RXH2 1/20 0.42
TSHR P16473 2/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
POLB P06746 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 2/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643555 0.88 L3MBTL1 (0.46) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL18050491 0.87 KDM4E (0.53) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL4646600 0.85 L3MBTL1 (0.46) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL4642260 0.85 L3MBTL1 (0.49) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL4641771 0.85 L3MBTL1 (0.44) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL4644486 0.84 L3MBTL1 (0.48) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL4646605 0.83 KDM4E (0.47) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL27619976 0.83 L3MBTL1 (0.47) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL2090857 0.81 KDM4E (0.44) L3MBTL1KDM4ETSHRMAPTMEN1
SCHEMBL28993234 0.81 THRB (0.58) L3MBTL1KDM4ETSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed