SCHEMBL4644486

SCHEMBL4644486

COC(=O)Cc1ccccc1OC(=O)CCl

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
TAAR1 Q96RJ0 1/20 0.43
KDM4E B2RXH2 1/20 0.42
TOP2A P11388 1/20 0.42
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647721 0.88 L3MBTL1 (0.46) L3MBTL1TAAR1KDM4ETOP2AMAPT
SCHEMBL18050491 0.87 KDM4E (0.53) L3MBTL1MTNR1AMTNR1BTAAR1KDM4E
SCHEMBL4642260 0.85 L3MBTL1 (0.49) L3MBTL1TAAR1KDM4EMAPTMEN1
SCHEMBL4645011 0.85 L3MBTL1 (0.44) L3MBTL1KDM4EMAPTMEN1TSHR
SCHEMBL4641986 0.84 L3MBTL1 (0.48) L3MBTL1TAAR1KDM4EMAPTMEN1
SCHEMBL4646605 0.83 KDM4E (0.47) L3MBTL1MTNR1AMTNR1BTAAR1KDM4E
SCHEMBL10389381 0.83 L3MBTL1 (0.44) L3MBTL1MTNR1AMTNR1BKDM4ETOP2A
SCHEMBL27619976 0.83 L3MBTL1 (0.47) L3MBTL1TAAR1KDM4EMAPTMEN1
SCHEMBL4646600 0.82 L3MBTL1 (0.46) L3MBTL1TAAR1KDM4EMAPTMEN1
SCHEMBL28448312 0.81 KDM4E (0.44) L3MBTL1TAAR1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed