SCHEMBL4642286

SCHEMBL4642286

CC[CH]C(=O)Oc1c(Cl)cc(Br)cc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.37
KDM4E B2RXH2 4/20 0.36
POLB P06746 1/20 0.36
THRB P10828 5/20 0.36
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
THRA P10827 4/20 0.33
GPR35 Q9HC97 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TPMT P51580 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642406 0.92 POLB (0.38) KDM4EPOLBTHRBMEN1KMT2A
SCHEMBL4647866 0.89 HSD17B10 (0.42) HSD17B10THRBMEN1KMT2ATHRA
SCHEMBL4644078 0.88 HSD17B10 (0.36) HSD17B10KDM4EPOLBTHRBMEN1
SCHEMBL4643493 0.83 HSD17B10 (0.40) HSD17B10KDM4EPOLBTHRBMEN1
SCHEMBL4644807 0.81 ERN1 (0.44) HSD17B10KDM4EPOLBTHRBMEN1
SCHEMBL4644487 0.80 POLB (0.36) KDM4EPOLBTHRBMEN1KMT2A
SCHEMBL4643896 0.79 KMT2A (0.36) KDM4EMEN1KMT2AALDH1A1TDP1
SCHEMBL4643215 0.77 HSD17B10 (0.43) HSD17B10KDM4EPOLBMEN1KMT2A
SCHEMBL4644186 0.76 HSD17B10 (0.40) HSD17B10KDM4EPOLBTHRBMEN1
SCHEMBL4641402 0.74 HSD17B10 (0.38) HSD17B10KDM4EPOLBTHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed