SCHEMBL4644487

SCHEMBL4644487

CCC[CH]C(=O)Oc1c(Cl)cc(Br)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
TSHR P16473 2/20 0.34
GPR35 Q9HC97 1/20 0.34
GALK1 P51570 1/20 0.33
ALDH1A1 P00352 5/20 0.32
KDM4E B2RXH2 3/20 0.32
KMT2A Q03164 4/20 0.31
GAA P10253 3/20 0.31
MEN1 O00255 3/20 0.31
MAPT P10636 2/20 0.31
THRB P10828 4/20 0.31
HTT P42858 3/20 0.31
THRA P10827 2/20 0.31
LMNA P02545 2/20 0.31
HPGD P15428 3/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644078 0.93 HSD17B10 (0.36) POLBTSHRGPR35ALDH1A1KDM4E
SCHEMBL4642406 0.87 POLB (0.38) POLBTSHRGPR35ALDH1A1KDM4E
SCHEMBL4643660 0.87 KMT2A (0.34) POLBGALK1ALDH1A1KDM4EKMT2A
SCHEMBL4644186 0.84 HSD17B10 (0.40) POLBALDH1A1KDM4EKMT2AGAA
SCHEMBL4642286 0.80 HSD17B10 (0.37) POLBTSHRGPR35ALDH1A1KDM4E
SCHEMBL4644362 0.78 POLB (0.40) POLBTSHRGPR35ALDH1A1KDM4E
SCHEMBL4645706 0.78 AHR (0.31) POLBGALK1KDM4EKMT2AMEN1
SCHEMBL4647606 0.77 ERN1 (0.41) ALDH1A1KDM4EKMT2AGAAMEN1
SCHEMBL4646065 0.73 MGLL (0.49) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL4643896 0.73 KMT2A (0.36) ALDH1A1KDM4EKMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed