SCHEMBL4642406

SCHEMBL4642406

CC[CH]C(=O)Oc1c(Cl)cc(Br)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GPR35 Q9HC97 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 4/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.33
THRB P10828 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 2/20 0.31
NMT1 P30419 1/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642286 0.92 HSD17B10 (0.37) POLBGPR35TSHRALDH1A1KDM4E
SCHEMBL4644487 0.87 POLB (0.36) POLBGPR35TSHRALDH1A1KDM4E
SCHEMBL4643896 0.86 KMT2A (0.36) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL4647866 0.83 HSD17B10 (0.42) ALDH1A1MEN1KMT2ALMNAGAA
SCHEMBL4644362 0.81 POLB (0.40) POLBGPR35TSHRALDH1A1KDM4E
SCHEMBL4644078 0.80 HSD17B10 (0.36) POLBGPR35TSHRALDH1A1KDM4E
SCHEMBL4641561 0.76 KMT2A (0.32) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL4644807 0.75 ERN1 (0.44) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL4641540 0.74 POLB (0.43) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL4643493 0.73 HSD17B10 (0.40) POLBTSHRALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed