SCHEMBL4642432

SCHEMBL4642432

c1ccc(Cc2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CALM1 P0DP23 1/20 0.48
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
GPR35 Q9HC97 2/20 0.46
POLB P06746 1/20 0.46
HSD17B10 Q99714 4/20 0.43
CYP1A2 P05177 3/20 0.43
CYP2C19 P33261 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C9 P11712 2/20 0.42
GPR55 Q9Y2T6 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23527435 0.92 HTR2A (0.48) HTR2AL3MBTL1CALM1APOBEC3AAPOBEC3G
SCHEMBL27959231 0.89 HTR2A (0.46) HTR2AL3MBTL1CALM1APOBEC3AAPOBEC3G
SCHEMBL23527407 0.88 HTR2A (0.48) HTR2AL3MBTL1APOBEC3AAPOBEC3GGPR35
SCHEMBL23527427 0.85 HTR2A (0.65) HTR2AL3MBTL1GPR35POLBHSD17B10
SCHEMBL23527443 0.84 CALM1 (0.46) HTR2AL3MBTL1CALM1APOBEC3AAPOBEC3G
SCHEMBL8866398 0.84 CYP1A2 (0.48) HTR2AL3MBTL1APOBEC3AAPOBEC3GGPR35
SCHEMBL1841464 0.83 CALM1 (0.61) CALM1MEN1KMT2AALDH1A1KDM4E
SCHEMBL28909736 0.82 HTR2A (0.47) HTR2AL3MBTL1APOBEC3AAPOBEC3GGPR35
SCHEMBL22685100 0.82 L3MBTL1 (0.43) HTR2AL3MBTL1GPR35POLBMEN1
SCHEMBL27476489 0.82 PARP1 (0.54) HTR2AL3MBTL1APOBEC3AAPOBEC3GGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
CN-114929158-B Method for producing denture, curable composition for photoforming, and kit for producing denture 株式会社德山齿科 2023-10-20 CN disclosed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
CN-114929158-A Method for producing a denture, curable composition for photo-molding, and kit for producing a denture 株式会社德山齿科 2022-08-19 CN disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
CN-108886103-A Charge-transporting varnish 日产化学株式会社 2018-11-23 CN disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-5049455-A Amphiphilic anthracene derivative KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-09-17 US disclosed
EP-0265373-B1 PROCESS FOR CURING POLYISOCYANATE COATINGS CIBA-GEIGY AG (CH) 1991-03-13 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
US-4861806-A PHOTOPOLYMERIZATION, LATENCY CIBA-GEIGY CORPORATION (US) 1989-08-29 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0265373-A1 Process for curing polyisocyanate coatings CIBA-GEIGY AG (CH) 1988-04-27 EP disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 HTR2A 2820/4885L3MBTL1 4367/4885CALM1 2648/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 HTR2A 2820/4885L3MBTL1 4367/4885CALM1 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.