SCHEMBL4642622

SCHEMBL4642622

O=C(CCCCl)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
GAA P10253 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.33
TRPA1 O75762 1/20 0.33
MAPK1 P28482 1/20 0.33
GSK3B P49841 1/20 0.33
HIF1A Q16665 1/20 0.33
RECQL P46063 1/20 0.33
NPC1 O15118 1/20 0.33
CRHBP P24387 1/20 0.33
RAB9A P51151 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646452 0.95 KMT2A (0.36) ALDH1A1GAASMN1; SMN2MAPTTDP1
SCHEMBL6555267 0.89 ALDH1A1 (0.35) ALDH1A1GAAMAPTTDP1L3MBTL1
SCHEMBL27601507 0.85 HPGD (0.38) ALDH1A1GAASMN1; SMN2MAPTTDP1
SCHEMBL4642474 0.84 MAPT (0.38) ALDH1A1GAASMN1; SMN2MAPTTDP1
SCHEMBL4644326 0.83 L3MBTL1 (0.37) ALDH1A1GAASMN1; SMN2MAPTTDP1
SCHEMBL4644017 0.83 PRSS1 (0.38) ALDH1A1SMN1; SMN2MAPTTDP1L3MBTL1
SCHEMBL28063157 0.83 KDM4E (0.50) ALDH1A1TDP1L3MBTL1KMT2AMEN1
SCHEMBL4644427 0.83 GPR84 (0.36) ALDH1A1GAASMN1; SMN2MAPTTDP1
SCHEMBL4641979 0.82 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2MAPTTDP1L3MBTL1
SCHEMBL4643834 0.80 TDP1 (0.36) ALDH1A1GAAMAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed